Streaming media over the Internet: Flow based analysis in live access networks

Multimedia service delivery over the Internet is a success. The number of services available and the number of people accessing them is huge. In this paper, we investigate multimedia streaming services over the Internet. Our analysis is based on traffic measurement in live access fiber-to-the-home networks. We study parameters like traffic volume and flow characteristics for selected services. Especially the Swedish P2P video service Voddler and the Swedish P2P music service Spotify are studied. We show that indeed these services are widely used (20% of local hosts using Voddler, 65 % of local hosts using Spotify). We also show that they are different concerning the flow characteristics, with many short flows for Voddler and longer flows for Spotify. One thing that they have in common in our measurements is that the outbound, or uplink, traffic volume is larger than the inbound

Leveraging network and traffic measurements for content distribution and interpersonal communication services with sufficient quality

In this paper, we discuss research problems for enabling content distribution and supporting real-time interpersonal communication services (e.g. voice and video) over best effort networks with sufficient quality. We take a practical view of content distribution and quality, and this is the reason for the term “sufficient”. We argue that the understanding of quality as perceived by the user is a key factor in this context, but also that the understanding of context dependence is a key factor for delivering services which are “good enough” to make the user satisfied. We base our assumptions upon results from the Celtic TRAMMS project, and we describe how to leverage upon the framework for traffic measurements that was built up in that project. Moreover, we identify key technological components that are common for optimization of content delivery and real-time interpersonal communication services such as VoIP and videoconferencing. We also describe how the research problems stated will be tackled in the newly started IPNQSIS project

Utilization of Quizizz as a Learning Medium for Elementary Teachers in Cisauk District

Digital competence is a competency that must be possessed by teachers in the digital era. However, this skill turned out to be a big obstacle during the covid-19 pandemic. Many teachers have not been able to take advantage of technology, so in learning, there are still those who rely on WhatsApp as a learning tool. Elementary school teachers in Cisauk District who are members of PGRI (Persatuan Guru Republik Indonesia) reported that student learning outcomes during the covid-19 pandemic were no better than before and they realized that students were less motivated. The purpose of this community service activity is to improve the knowledge and ability of teachers in Cisauk District in using Quizizz. This activity was held in virtual training for 46 teachers and school principals. The methods used are discussion, demonstration, assignment, monitoring, mentoring, and evaluation. The teacher is given the task of making a Quizizz and testing it for their students in class. Teachers are also accompanied and guided in completing assignments. From the results of the training, teachers showed an increase in knowledge and skills using Quizizz. Quizizz also has a positive response from students

A five year perspective of traffic pattern evolution in a residential broadband access network

In this paper we describe a systematic study on long-term evolution of residential broadband Internet traffic covering 5 calendar years from June 2007 to May 2011. The traffic evolution is characterized both in the term of the total traffic volume, as well as the traffic volumes and shares for different application categories (file sharing, video streaming etc.), with the focus on comparing the traffic on the per IP user basis and among different broadband subscription groups. The results show that the average daily total traffic generated by each private end user increased only by about 33 % during the past 5 years. Further, the results show that the P2P filesharing has been dominating the network total traffic, but the daily file-sharing traffic volume per end user largely remains the same. Also, the daily streamingmedia traffic volume per end user has increased dramatically by over 500% during the studied period of time. In the meantime, the daily web-browsing traffic volume per end user has increased by about 300%. Finally, a further investigation among 4 different FTTH broadband subscription groups with 1, 10 , 30, and 100 Mbit/s symmetric access speeds shows that the lower the access speed, the more diversified the end user traffic tend to be

Analysis of Facebook content demand patterns

Data volumes in communication networks increase rapidly. Further, usage of social network applications is very wide spread among users, and among these applications, Facebook is the most popular. In this paper, we analyse user demands patterns and content popularity of Facebook generated traffic. The data comes from residential users in two metropolitan access networks in Sweden, and we analyse more than 17 million images downloaded by almost 16,000 Facebook users. We show that the distributions of image popularity and user activity may be described by Zipf distributions which is favourable for many types of caching. We also show that Facebook activity is more evenly spread over the day, compared to more defined peak hours of general Internet usage. Looking at content life time, we show that profile pictures have a relatively constant popularity while for other images there is an initial, short peak of demand, followed by a longer period of significantly lower and quite stable demand. These findings are useful for designing network and QoE optimisation solutions, such as predictive pre-fetching, proxy caching and delay tolerant networking

YouTube Traffic Content Analysis in the Perspective of Clip Category and Duration

In this work, we study YouTube traffic characteristics in a medium-sized Swedish residential municipal network that has 2600 mainly FTTH broadband-connected households. YouTube traffic analyses were carried out in the perspective of video clip category and duration, in order to understand their impact on the potential local network caching gains. To the best of our knowledge, this is the first time systematic analysis of YouTube traffic content in the perspective of video clip category and duration in a residential broadband network. Our results show that the requested YouTube video clips from the end users in the studied network were imbalanced in regarding the video categories and durations. The dominating video category was Music, both in terms of the total traffic share as well as the contribution to the overall potential local network caching gain. In addition, most of the requested video clips were between 2-5 min in duration, despite video clips with durations over 15 min were also popular among certain video categories, e.g. film videos

A global customer experience management architecture

Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. A. Cuadra-Sanchez, M. Cutanda-Rodriguez, I. Perez-Mateos, A. Aurelius, K. Brunnstrom, J. Laulajainen, M. Varela, and J. E. López de Vergara, "A global customer experience management architecture", in Future Network and Mobile Summit, 2012, 1-8The quality of experience (QoE) is one of the main research lines in ITC industry, which seeks to manage quality as perceived by users. This document analyzes and describes requirements of a QoE driven management system architecture, which has been designed in the Celtic IPNQSIS project. The architecture is grouped into different levels: Data acquisition level, Monitoring level and Control Level. Each level comprises a specific set of capacities, such as Data collector, or Traffic Monitor amongst others. The architecture described in this paper constitutes the guidelines of the IPNQSIS project in terms of a QoE ecosystem that will settle the basis of global customer experience management architecture.This work is carried out in the framework of the Celtic and EUREKA initiative IPNQSIS (IP Network Monitoring for Quality of Service Intelligent Support) and has been partially funded by CDTI under Spanish PRINCE (PRoducto INdustrial para la gestión de la Calidad de Experiencia) project, meanwhile the Swedish part of the project is co funded by VINNOVA and the work of Finnish partners has been partially funded by Tekes

First-in-Human Phase I Study of MP0250, a First-in-Class DARPin Drug Candidate Targeting VEGF and HGF, in Patients With Advanced Solid Tumors.

PURPOSE: A first-in-human study was performed with MP0250, a DARPin drug candidate. MP0250 specifically inhibits both vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) with the aim of disrupting the tumor microenvironment. PATIENTS AND METHODS: A multicenter, open-label, repeated-dose, phase I study was conducted to assess the safety, tolerability, and pharmacokinetics of MP0250 in 45 patients with advanced solid tumors. In the dose-escalation part, 24 patients received MP0250 as a 3-hour infusion once every 2 weeks at five different dose levels (0.5-12 mg/kg). Once the maximum tolerated dose (MTD) was established, 21 patients were treated with a 1-hour infusion (n = 13, 8 mg/kg, once every 2 weeks and n = 8, 12 mg/kg, once every 3 weeks) of MP0250 in the dose confirmation cohorts. RESULTS: In the dose-escalation cohort, patients treated with 12 mg/kg MP0250 once every 2 weeks experienced dose-limiting toxicities. Therefore, MTD was 8 mg/kg once every 2 weeks or 12 mg/kg once every 3 weeks. The most common adverse events (AEs) were hypertension (69%), proteinuria (51%), and diarrhea and nausea (both 36%); hypoalbuminemia was reported in 24% of patients. Most AEs were consistent with inhibition of the VEGF and HGF pathways. Exposure was dose-proportional and sustained throughout the dosing period for all patients (up to 15 months). The half-life was about 2 weeks. Signs of single-agent antitumor activity were observed: 1 unconfirmed partial response with a time to progression of 23 weeks and 24 patients with stable disease, with the longest duration of 72 weeks and a median duration of 18 weeks. CONCLUSION: MP0250 is a first-in-class DARPin drug candidate with suitable tolerability and appropriate pharmacokinetic properties for further development in combination with other anticancer therapies

Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis

Herpes simplex encephalitis (HSE) is a rare complication of Herpes simplex virus type-1 infection. It results in severe parenchymal damage in the brain. Although viral latency in neurons is very common in the population, it remains unclear why certain individuals develop HSE. Here we explore potential host genetic variants predisposing to HSE. In order to investigate this we used a rat HSE model comparing the HSE susceptible SHR (Spontaneously Hypertensive Rats) with the asymptomatic infection of BN (Brown Norway). Notably, both strains have HSV-1 spread to the CNS at four days after infection. A genome wide linkage analysis of 29 infected HXB/BXH RILs (recombinant inbred lines-generated from the prior two strains), displayed variable susceptibility to HSE enabling the definition of a significant QTL (quantitative trait locus) named Hse6 towards the end of chromosome 4 (160.89-174Mb) containing the Vwf (von Willebrand factor) gene. This was the only gene in the QTL with both cis-regulation in the brain and included several non-synonymous SNPs (single nucleotide polymorphism). Intriguingly, in human chromosome 12 several SNPs within the intronic region between exon 43 and 44 of the VWF gene were associated with human HSE pathogenesis. In particular, rs917859 is nominally associated with an odds ratio of 1.5 (95% CI 1.11-2.02; p-value = 0.008) after genotyping in 115 HSE cases and 428 controls. Although there are possibly several genetic and environmental factors involved in development of HSE, our study identifies variants of the VWF gene as candidates for susceptibility in experimental and human HSE